Blog

Heart & Cardiovascular Disease

Posted February 6, 2019 in: Uncategorized

One in three Americans get it. It is preventable and reversible… if you take action!

Basic cardiac risks

  • History of Heart Disease, MI, CABG, PTCA-Stent, stroke, peripheral arterial disease.
  • Family history of Heart Disease- male before age 55, female before age 65.
  • Your age- >45 for men; >55 for women.
  • Sedentary lifestyle (minimal exercise)
  • Obesity
  • Smoking
  • Hypertension
  • Pre-Diabetes/Diabetes

Take home: Primary line of defense is diet and lifestyle changes!

Understanding the cause

  • The initiation of damage to the endothelial inner arterial wall occurs from sugars and processed foods, from toxins (metals/chemicals) from infections (gums, teeth, and gut), high blood pressure, and stress. The Standard American Diet results in nutritional deficiencies preventing healing.
  • Inflammation/oxidation occurs to mend injured tissue and is the very first healing reaction.
  • Cholesterol acts as an anti-oxidant, gets oxidized, and then gets stuck at the site of injury. It is secondary to inflammation. If cholesterol was primary then the number or heart attacks would be increased with higher levels. These are equal to the number of heart attacks with low or high cholesterol.
  • High sugars, high insulin, high blood pressure, high inflammation, toxins, and stress are priority.
  • Lowering cholesterol/ particles does not treat the cause it does not prevent heart disease nor arterial plaque resolution.
  • Arterial plaques are 3% cholesterol and up to 50% calcium.
  • The only reason statin drugs help is due to their small effect on inflammation and viscosity, not by lowering cholesterol.
  • The initiation of mitochondrial disruption occurs from the same causes of endothelial dysfunction
  • The lipid hypothesis of lowering cholesterol intake and saturated fats never worked because it never treated the causes of cardiovascular disease.

 

A second look at cardiac risks using labs & other tests

Blood test indications- 50% of patients who suffer a heart attack have normal cholesterol, and 50% of people with high LDL have healthy hearts. A large percentage of women with CVD have clear coronary arteries on angiograms.

  1. Inflammation
    1. Hs CRP – Systemic
    2. Lp PLA2 – Arterial plaque
    3. Myeloperiodase – arterial plaque
    4. IL-6- inflammatory cytokine
  2. Metabolic/Glucose
    1. Fasting glucose and insulin
    2. 2 hours after eating- glucose and insulin levels
    3. Glycohemoglobin A1C
    4. Uric acid level
    5. Chemistries, electrolytes, RBC magnesium
    6. Urine microalbumin
    7. Ferritin
    8. Calcium/phosphorus ratio
  3. Viscosity/ sticky blood
    1. Fibrinogen level
    2. Lipoprotein(a)
    3. Homocysteine
    4. Urinary F2-isoprostanes
  4. Stress/ Hormone Input
    1. DHEA-S
    2. Free + total testosterone, estradiol level, sHBG
    3. Extra- dihydrotestosterone, progesterone
    4. Thyroid function tests
  5. Low oxygen/ anemia
    1. Vo2 (oxygen utilization test)
    2. Oxygen saturation
  6. Endothelial function
    1. Max pulse- photoplethysmography (arterial elasticity)
    2. Nitric oxide level- saliva strips
  7. Plaque size/ progression
    1. Coronary artery calcification score
    2. Carotid intima-medial thickness (cumulative effects of years of endothelial dysfunction)
    3. Cardiac muscle – troponin, ckmb, nt-pro BNP, CoEnzymeQ10, Lactic Acid Dehydrogenase (LDH)
  8. Cholesterol
    1. Fasting lipid panel
    2. Apo B level
    3. Oxidized LDL
  9. Fats
    1. Phase angle (bioimpedance electrical analysis)
    2. Omega score- omega 6 to omega 3 index
  10. Weight (waist, BMI)
  11. Blood pressure & heart rate
  12. Arrhythmia –
    1. Holter monitor
    2. EKG
  13. Heart rate variability test reflects the Autonomic Nervous System
  14. Nutritional analysis by Heart Sound Recorder & kinesiology testing
  15. Dental/oral cavity
    1. Gut and oral health by kinesiology testing
    2. Microbiome lab testing
  16. Other:
    1. 25OH Vit D3
    2. Serum Amyloid A

 

A Second Word on Diet

  1. Eliminate/ Dump it:
    1. Sugar, soda, fruit juices, energy drinks, high fructose corn syrup
    2. Processed carbs (ie. Cereals)
    3. Trans fats- non dairy creamers, margarine, Wesson Crisco, corn oil, soy oil, canola oil, baked goods, ramen noodles
    4. Processed meats- deli meats
    5. Excess vegetable oils
  2. Eat:
    1. Wild Alaskan salmon or other wild caught seafood (not farm raised) 2x/week
    2. Berries- blueberries, blackberries, strawberries, raspberries, and cherries
    3. 5-9 servings of vegetables/day – bring the vegetable market home
    4. Nuts- an assortment 1-2oz, 3x per week
    5. Increase fiber 30g/day
    6. Buy organic
    7. Filtered water
    8. Alternate coffee with green tea & hibiscus tea
    9. Pastured organic poultry (chicken, turkey, etc.)
    10. Pastured grass-fed organic meats (beef, buffalo, lamb)
    11. Pomegranate juice and beet powder
    12. A Quick Word on Fats
  1. Saturated Fats
    1. increase total cholesterol, HDL, and fluffy LDL
    2. Hard to damage & good for cooking
  2. Monounsaturated fats- olive oil
  3. PUFA- polyunsaturated fats: omega 3 + omega 6
    1. Omega 6 fats are vegetable oils and are pro-inflammatory: corn oil, soy oil, peanut oil, canola oil
    2. Omega 3 fats are flax seed oil, seafood, and grass-fed beef- all are anti-inflammatory
    3. Omega 6 to omega 3 ratio is very important. Goal is 1/1 up to 4/1
  4. Trans fats- very inflammatory- causing heart disease, DM2, and cancer

Take home:

  • Eliminate sugar and processed carbs.
  • Eliminate trans fats
  • Increase omega 3, decrease omega 6.
  • Cholesterols and saturated fats have a minor role in heart disease
  • There are 3 reasons why a low fat, high carb diet works some of the time: A large drop in omega 6, low in sugar, and less high glycemic carbs.

Statin Drugs

  • Lowers CRP and decreases blood viscosity and cholesterol
  • 15 of 16 studies using drugs to lower cholesterol showed no benefit for heart disease
  • In the “heart protection study” the absolute risk reduction was only 1.8% decrease. There was no change in mortality and no change in primary prevention.
  • Jupiter trial showed ARR of < 1 %, diabetes increased and there was no change in plaque progression or size.
  • Only men with prior cardiovascular disease age 40-70 saw small benefit

Take Home: Primary line of defense is diet and lifestyle changes

 

Work Sheet

  1. Diet & nutrition:
    1. Must handle sugars/carbohydrates
    2. Generate energy/ Maximize mitochondrial function and numbers
    3. Optimize heart nutrition
  2. Handle inflammation and toxicity
  3. Treat viscosity and sticky blood
  4. Handle stress/ lifestyle/ great sleep
  5. Improve oxygenation
  6. Maximize endothelial function
  7. Reduce arterial plaques
  8. Balance omega 6 and omega 3
  9. Lower oxidized LDL
  10. Change weight & BP with lifestyle changes
  11. Optimize fats, hormones, and electrolytes for electrical conduction
  12. Handle gut and oral cavity